Formulation and Evaluation of Herbal Gel for Mouth Ulcer

Mouth ulcers are common inflammatory lesions of the oral cavity that cause pain, discomfort, and difficulty in eating and speaking. Conventional therapies provide symptomatic relief but may produce side effects during prolonged use. The present study aimed to formulate and evaluate a herbal gel containing Combretum indicum leaf extract for the treatment of mouth ulcers. The extract was prepared using hydroalcoholic extraction and incorporated into a Carbopol 934 gel base. The formulated gel was evaluated for organoleptic properties, pH, homogeneity, spreadability, stability, and antimicrobial activity. The optimized formulation showed satisfactory physicochemical properties with good spreadability, pH compatibility, stability, and antimicrobial activity against oral pathogens. The study suggests that Combretum indicum-based herbal gel may serve as a safe, effective, and economical alternative for the management of mouth ulcers.