First-in-human evaluation of 6-bromo-7-[11C]methylpurine, a PET tracer for assessing the function of multidrug resistance-associated proteins in different tissues

Severin Mairinger; Matthias Jackwerth; Zacharias Chalampalakis; Ivo Rausch; Maria Weber; Michael Wölfl‐Duchek; Lena Pracher; Lukas Nics; Jens Pahnke; Werner Langsteger; Marcus Hacker; Markus Zeitlinger; Oliver Langer

doi:10.1007/s00259-024-06851-2

July 26, 2024European Journal of Nuclear Medicine and Molecular ImagingOpen Access

First-in-human evaluation of 6-bromo-7-[11C]methylpurine, a PET tracer for assessing the function of multidrug resistance-associated proteins in different tissues

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Abstract

Multidrug resistance-associated protein 1 (MRP1) is a transport protein with a widespread tissue distribution, which has been implicated in the pathophysiology of Alzheimer's and chronic respiratory disease. PET with 6-bromo-7-[

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Mairinger et al. (2024) studied this question.

synapsesocial.com/papers/68e5ee87b6db64358758307b https://doi.org/10.1007/s00259-024-06851-2

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First-in-human evaluation of 6-bromo-7-[11C]methylpurine, a PET tracer for assessing the function of multidrug resistance-associated proteins in different tissues

Abstract

Discussion

Cite This Study

First-in-human evaluation of 6-bromo-7-[11C]methylpurine, a PET tracer for assessing the function of multidrug resistance-associated proteins in different tissues

Abstract

Discussion

Cite This Study

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