The relations between AD and DS and the therapies for curing this disease

Down syndrome is a disease that has relations with Alzheimers disease. In this work, it mainly focus on the mechanism of additional 21st chromosome in Down syndrome patients causes the rise of A protein (a protein would cause Alzheimers disease). Two diseases that would reduce the life expectancy and loss of memory. This paper also discuss the exist therapy for curing Alzheimers disease in Down syndrome by choline supply during pregnancy, using acetylcholinesterase for inhibiting and secondary prevention in experiment on Ts65Dn mice. Results show that though the samples size is small, some side effects are caused and there is no specific results show that those therapies is also useful in clinic trials, the great success is achieved in animal lines (near 50% to 60% of success). These therapies can play a significant role in the future and it can reduce the impact of Down syndrome and Alzheimers disease in patients.