Background & Objective: Grahani Roga is considered a Tridoshatmaka disorder of the digestive system, directly related to the status of Agni and diet habits, which occurs due to the vitiation of Agni (Mandagni) and Doshas. Gandhaka Rasayana is a standard Herbo-mineral formulation of Ayurveda, used extensively in treating various skin, wound and gastrointestinal disorders. It was believed to be significant in Amapachana, Agnideepana, Rasayana, Raktaprasadana, Kledaghna, and Krimihara activity. In this study, we evaluated the effect of Gandhaka Rasayana in the management of Grahani Roga. Materials & Methods: The trial drug Gandhaka Rasayana was administered 500 mg twice a day to 90 selected patients of Grahani Roga. After 45 days of trial, the effectiveness of Gandhaka Rasayana was statistically evaluated based on various parameters, such as Subjective, Clinical, and Objective improvement. Results and Conclusion: Gandhaka Rasayana was found statistically highly significant in the Clinical Symptoms of Grahani Roga, with 38.39% average improvement; it also had a significant effect on Agni Bala and Deha Bala, with 48.81% and 39.09% average improvement, respectively. Hence, the overall average effect on parameters of clinical improvement after the therapeutic trial of Gandhaka Rasayana in 90 patients of Grahani Roga was 42.09%. Thus, Gandhaka Rasayana is a very potent drug and can be used effectively in the management of Grahani Roga.
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Kumar et al. (2024) studied this question.
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