Observational multi-center study evaluates machine-learning prediction of disability progression in multiple sclerosis, highlighting the need for clinical benchmarks.
Disability progression is a key milestone in the disease evolution of people with multiple sclerosis (PwMS). Prediction models of the probability of disability progression have not yet reached the level of trust needed to be adopted in the clinic. A common benchmark to assess model development in multiple sclerosis is also currently lacking.
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Brouwer et al. (2024) studied this question.
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