T-cell dysfunction in CLL is mediated through expression of SIGLEC-10 ligands CD24 and CD52 on CLL cells

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1The complexities of T-cell dysfunction in chronic lymphocytic leukemia2024 · 4 citations
2. 2T-cell immunosenescence limits CD19 CAR T-cell function in chronic lymphocytic leukemia2026
3. 3Functional differences between CLL‐ and ALL‐derived CAR T cells in a 3D tumor microenvironment highlight CXCR4 and IL‐10 as potential modulatory targets2025 · 2 citations
4. 4Cholesterol homeostasis and lipid raft dynamics at the basis of tumor-induced immune dysfunction in chronic lymphocytic leukemia2025 · 19 citations
5. 5IL‑10 limits CLL progression by reprogramming T cell exhaustion and myeloid suppression2025