Significant progress has been made in the field of gastroretentive drug delivery systems using natural polysaccharides. These improvements aim to improve the effectiveness and absorption of different medicinal agents. Pectin has received substantial attention in recent years due to its dis-tinctive structural characteristics, abundant availability, biocompatibility, lack of toxicity, and wide range of applications. The global utilization of pectin in drug delivery systems has expanded signifi-cantly. Pectin is used to achieve flotation and mucoadhesive properties, which enhance gastric resi-dence length and improve therapeutic effectiveness. The article aims to comprehensively examine the information on several pectin-based formulations for medication delivery that are designed to remain in the stomach for an extended period of time. Furthermore, this article emphasizes the diverse physicochemical and biological properties of pectin and modified pectin, as well as their prospective uses in numerous fields. This publication also presents the significant advantages, challenges, poten-tial future developments, and patents on pectin-based gastroretentive drug delivery systems.
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Pahwa et al. (2024) studied this question.
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