Crosstalk Between MAPK and PI3K/AKT Signaling Pathways in Cellular Responses: Implications for Cancer Therapy

This research paper aims to explore the intricate crosstalk between the mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) signaling pathways. These pathways play crucial roles in regulating cellular processes such as growth, proliferation, survival, and apoptosis. Dysregulation of these pathways is commonly associated with the development and progression of various cancers. By understanding the mechanisms of crosstalk between MAPK and PI3K/AKT pathways, this study seeks to identify potential therapeutic targets and strategies for more effective cancer treatment.