Figure 4 from Putrescine Supplementation Limits the Expansion of pks+ Escherichia coli and Tumor Development in the Colon

Gut microbiota modulation by putrescine supplementation in the AOM/DSS mouse model of colitis-associated colorectal CRC. A, Chao1, ACE, and Shannon indexes at day 70 (mean ± SEM, t test). B, Principal coordinate analysis (PCoA) of the unweighted UniFrac and Bray–Curtis distances. C, Differential bacterial abundance at the phylum and genus levels (mean ± SEM, FDR corrected). Bar graphs of relative abundances at the phylum level at day 70. Each stacked bar represents a single mouse. N = 8–9 mice per group.