Answers are grounded in this paper and cite their sources.
Tenofovir disoproxil fumarate (TDF) compared to tenofovir alafenamide (TAF) leads to lower body weight and plasma lipids by an unknown mechanism. We hypothesize that TDF, when absorbed, may damage enterocytes of the proximal duodenum, leading to reduced absorption of nutrients.
No takes yet. Share an insight, caveat, or question.
Kauppinen et al. (2024) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: