Dexamethasone intravitreal implant for retinitis pigmentosa combined with macular edema：A case report

Abstract RP is a highly blinding disease, with central vision often impaired when accompanied by macular oedema, for which there is no clear and effective treatment. Current treatment options include oral and topical carbonic anhydrase inhibitors, oral, topical, intravitreal, periocular injections of steroids, topical nonsteroidal anti-inflammatory drugs, retinal laser photocoagulation, vitrectomy and inner border membrane peeling, oral lutein, and intravitreal anti-vascular endothelial growth factor injections. We report a case of a patient who was given bilateral vitreous injections of dexamethasone intravitreal implant.We report the case of a 33-year-old male with night blindness since childhood, blurred vision in both eyes for more than 3 months, previously healthy, with peripheral retinal osteoclastic pigmentation, small retinal arteries, and thickening of retinal oedema in the macula.OCT showed cystic changes in the macula in both eyes, FFA exhibited an increased level of fluorescence leakage in both the left and right eyes. Petal-like fluorescence accumulation was seen in the macular area in the late stage, which led to the diagnosis of bilateral retinitis pigmentosa with macular oedema in both eyes. Best-corrected visual acuity improved and macular oedema were subsided after about two months of treatment, and Ozurdex might be useful in the treatment of retinitis pigmentosa with macular oedema.