Evaluation of Pediatric Common Solid Small Round Cell Tumors: An Immunohistochemical Study

due to their primitive character. With the rising incidence and having better treatment outcome ascompared to the past, the categorization of SRCTs into definitive histological types is extremelyimportant as individual tumor differs therapeutically and has separate prognostic significance.Immunohistochemistry (IHC) can play an important role here.Objective: The present study was designed to evaluate the role of immunohistochemistry (IHC) inthe differential diagnoses of pediatric SRCTs.Results: In this study, various histomorphological types of pediatric SRCTs were identified inabout 97% of cases with the aid of immunohistochemical stains. However, about 3% of casesremain unclassified even after immunohistochemical tests. The different morphological patternswere as follows; 24.4% rhabdomyosarcoma, 22.2% lymphoblastic lymphoma, 22.2%neuroblastoma, 22.2% soft tissue Ewing sarcoma, 4.44% Wilms Tumor, and 1.48% poorlydifferentiated synovial sarcoma.Conclusion: Immunohistochemistry plays an important role as is evident from the present studyand supported by many previous studies in categorizing undifferentiated or poorly differentiatedsmall round cell tumors of childhood.