Cytopathological Analysis of Oral Buccal Mucosa of Dental College Students

In this study Cytopathological observations were recorded, including inflammation, microbial colonies, micronuclei, keratinisation, overlapping and hemorrhage of cells which are obtained from the buccal mucosa of the dental students to assess the fluctuation of the cellular characteristics among relatively normal subjects. This prospective study included 50 dental students with no detectable oral alterations and are submitted to brush cytology. The smears were fixed with 95% ethyl alcohol and stained with hematoxylin and eosin stain. The stained section were observed. Chi-square tests were applied for non-parametric variables. A p-value < 0.05 was considered statistically significant. The results showed close proximity among subjects in the matter of cytopathological observation and measures; no significant influence of sex was found on cytopathological observation, and vice versa. Oral exfoliative cytology combined with cytopathological analysis can be helpful for the study of normal individuals in various investigations of oral and systemic diseases.