The use of brain organoids in Alzheimer’s disease (AD) research has shown promising results in recent years. Studies have demonstrated the potential of cerebral organoids to model early pathogenesis of AD, evaluate drug effectiveness, and identify early alterations associated with the disease. These advancements highlight the utility of brain organoids in drug screening, examining specific compounds’ effects, and modeling disease-related changes such as mitophagy alterations. Additionally, the use of retinal organoids has provided insights into early changes within the central nervous system and their implications for early AD diagnosis.
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S. Rahimian (2024) studied this question.
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