Undesirable side reactions when introducing intradermal implants based on hyaluronic acid

Over the past two decades, there has been an increase in the popularity of procedures using hyaluronic acid-based products. In parallel with this, the number of drugs with insufficiently purified hyaluronic acid is growing, in order to reduce the cost of the product, which leads to the development of unwanted adverse reactions (ADRs). The pathogenesis of some reactions is not fully understood, which makes their diagnosis and treatment difficult. The article discusses the types of NPD, factors influencing their development, as well as options for their correction.