Figure 3 from Noninvasive Lung Cancer Subtype Classification Using Tumor-Derived Signatures and cfDNA Methylome

Classification of lung cancer subtypes using plasma cfDNA. A, ROC curve of subtype classification on plasma cfDNA. The performance of the subtype classification model was evaluated using LOOCV. The bold curves are the ROC curve. The colored areas represent the CI of the ROC curve. B, Accuracy of the subtype classification. Accuracy was evaluated on the plasma samples with detectable and undetectable tumor fractions, as estimated using ichorCNA. C, ROC curve of subtype classification on an independent validation set.