Clinical Evaluation of Sushvikadi Vati in Purishaja Krimi(pin Worm) (A Study Protocol)

The term "Krimi" in Ayurveda refers to all worms and microbes. The concept of krimi is not new; references to it date back to the Vedic era. The literature on Ayurveda describes the visible and invisible, or macro and micro, organisms that impact both living and non-living objects in the biosphere. In contemporary medical science, worms and bacteria are studied under different branches called helminthology and microbiology, respectively. However, in Ayurveda, the term "Krimi" refers to both types of worms and microbes. All acharyas in Ayurveda used the name "Krimi," and the majority of authors explained the term's classification, causes, symptoms, and treatments. Ayurvedic doctors have an understanding of Krimis and Krimi rogas ; they have identified as different varieties of Krimis.Thus, in the present study Purishaja Krimi(Pin worm) is taken as the subject of intervention with the drug ‘Sushvikadi Vati’ mentioned in a Arogya Raksha Kalpadrumah, krimi rog chikitsa adhyaya 10) MATERIALS AND METHODS : This prospective, open label, randomized clinical trial will be conducted at, School Of Ayurveda D.Y. Patil Deemed To Be University Navi Mumbai. A total of 60 children of aged 4-13 years irrespective of gender with classical symptoms of Purishaja Krimi (Pin worm )will be enrolled in the study. The outcome will be assessed according to the subjective and objective parameters established respective-ly for the study on each visit. Safety will be assessed based on the incidence of adverse events. DISCUSSION AND CONCLUSION: Krimi is the disease of GIT, and it has aaharaj and viharaja Nidana and its samprapti involves vitiation of Tridosha . Its samprapti involves agnimandya and mala dravata and the Ayurvedic formulation chosen for this study, “SUSHVIKADI VATI” usually have Krimighna property out-comes of this trial will suggest probable therapeutic options for the effective management of krimi of children.