⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

July 15, 2024Frontiers in Aging NeuroscienceOpen Access

Genetic link between KIF1A mutations and amyotrophic lateral sclerosis: evidence from whole-exome sequencing

Wei Zheng Ji He Lu Chen Weiyi Yu Nan Zhang Xiaoxuan Liu Dongsheng Fan

View Full Paper

Ask AI

Bookmark

Share

Abstract

Genetics have been shown to have a substantial impact on amyotrophic lateral sclerosis (ALS). The ALS process involves defects in axonal transport and cytoskeletal dynamics. It has been identified that

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Zheng et al. (2024) studied this question.

synapsesocial.com/papers/68e60461b6db64358759756f https://doi.org/10.3389/fnagi.2024.1421841

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Whole-Genome Sequencing Identified a Novel Mutation in the N-Terminal Domain of KIF5A in Chinese Patients with Familial Amyotrophic Lateral Sclerosis2024
2KIF5A and ALS: a clinical and genetic description of a case series and review of literatureCase Report · 2026 · 1 citations
3A Novel De Novo Missense Mutation in KIF1A Associated with Young-Onset Upper-Limb Amyotrophic Lateral Sclerosis2024 · 5 citations
4A Novel de Novo Missense Mutation in KIF1A Associated with Young-Onset Upper-Limb Amyotrophic Lateral Sclerosis2024 · 1 citations
5KIF1A, R1457Q, and P1688L Mutations Induce Protein Abnormal Aggregation and Autophagy Impairment in iPSC-Derived Motor Neurons2024 · 1 citations