Objective: To estimate the accuracy of MRI in diagnosing and differentiating between orbital lymphoma and pseudotumors with histopathological correlation. Materials And Methods: This prospective analytical study was conducted in the Radiology department of a tertiary-care hospital and included 21 patients referred from the Ophthalmology department whose MRI was done in our department and a diagnosis of lymphoma or pseudotumor was given. These patients were followed up to obtain a nal diagnosis. Results: Of the 21 patients, 10 patients were conrmed to have pseudotumors and 11 patients were conrmed to have lymphoma. MRI correctly identied pseudotumors in 7 out of 10 patients and ruled them out in 8 out of 11 patients. Similarly, MRI identied lymphoma correctly in 8 out of 11 patients and ruled it out in 7 out of 10 patients. Sensitivity and specicity were calculated for the results with 95% condence intervals. Conclusion: T2-weighted images in MRI are most useful in differentiating lymphoma from pseudotumor with a sensitivity of 70% and specicity of 72.7%. Further studies with advanced sequences like DWI, perfusion and dynamic contrast may help in increasing the diagnostic accuracy of MRI.
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Sabnis et al. (2024) studied this question.
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