We explore the information which proposed matterwave interferometry experiments with large test masses can provide about parameterizable extensions to quantum mechanics, such as have been proposed to explain the apparent quantum to classical transition. Specifically, we consider a matterwave near-field Talbot interferometer and Continuous Spontaneous Localization (CSL). Using Bayesian inference we compute the effect of decoherence mechanisms including pressure and blackbody radiation, find estimates for the number of measurements required, and provide a procedure for optimal choice of experimental control variables. We show that in a simulated space-based experiment it is possible to reach masses of <a:math xmlns:a="http://www.w3.org/1998/Math/MathML"><a:mrow><a:mo>∼</a:mo><a:msup><a:mn>10</a:mn><a:mn>9</a:mn></a:msup><a:mspace width="0.16em"/><a:mspace width="4.pt"/><a:mtext>u</a:mtext></a:mrow></a:math>, and we quantify the bounds which can be placed on CSL. These specific results can be used to inform experimental design, and the general approach can be applied to other parameterizable models. Published by the American Physical Society 2024
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