Oral squamous cell carcinoma in Mexican population. Characterization and analysis of a 13-year period

Background: Oral squamous cell carcinoma (OSCC) is a malignant epithelial neoplasia.Objective: To analyze the prevalence of demographic, clinical and histopathological characteristics of OSCC in a Mexican population over a period of 13 years.Method: The pathology service files were reviewed, and OSCC diagnosed from 2007 to 2020 were identified, as well as available demographic and clinical information.Results: Of 40,606 biopsies, 143 OSCC were identified, and 60.1% were in men; the mean age was 63.8 years.Regarding the location, the most frequent sites were the lip region 27%, followed by the tongue 23.07%, and the gingiva 17.4%; 100% of men reported consuming or having consumed alcohol and tobacco, compared to 38.5% of women in relation to alcohol and 47.3% in relation to tobacco.According to the histological grade, 67.8, 23.1, and 9.09% corresponded to the well differentiated, moderately differentiated, and poorly differentiated type, respectively.Conclusions: Our results show that the clinical and histopathological characteristics as well as the risk factors in a Mexican population affected by OSCC, are in accord with the risk and clinical factors reported in the literature.