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July 11, 2024

Single-Cell, Single-Nucleus and Xenium-Based Spatial Transcriptomics Analyses Reveal Inflammatory Activation and Altered Cell Interactions in the Hippocampus in Mice with Temporal Lobe Epilepsy.

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Authors

QLQuanlei LiuCSChunhao ShenYDYang Dai

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Cite This Study

Liu et al. (2024) studied this question.

synapsesocial.com/papers/68e60ac3b6db64358759db56https://doi.org/10.21203/rs.3.rs-4590465/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Single-cell, single-nucleus and xenium-based spatial transcriptomics analyses reveal inflammatory activation and altered cell interactions in the hippocampus in mice with temporal lobe epilepsy2024 · 9 citations
  2. 2Single-nucleus transcriptomics reveals cell type-specific remodeling and epilepsy-associated microglia2026
  3. 3Spatiotemporal transcriptomic mapping reveals region-specific glial activation and astrocyte shifts in epileptogenesis beyond the hippocampus2026 · 1 citations
  4. 4Integrative Transcriptomic Mapping Reveals C1Q/AP-Like Microglial State Reconfiguration in Temporal Lobe Epilepsy with Hippocampal Sclerosis2026
  5. 5Exploratory Single-Nucleus RNA Sequencing Suggests Glial-Specific NPY Upregulation and Cell-Type-Specific Metabolic Alterations in Temporal Lobe Epilepsy2026