Unravelling the potential of hydrogen in biological systems

Molecular hydrogen (H2) and oxyhydrogen (66% H2/ 33% O2) gases have been demonstrated to remediate the effects of numerous diseases in adults[1-4]. By acting as an anti-inflammatory and antioxidative agent, it is reported that H2 can improve recovery through mitigating hyperinflammatory responses and reducing oxidative stress[5-7]. As the precise mechanisms of H2 activity are currently undefined, the lack of primary target identification, coupled with difficulties regarding administration methods (e.g., dosage and dosage frequencies, and long-term effects of treatments), there is a requirement for H2 research to evidence how it can reasonably and effectively, be incorporated into healthcare.