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July 8, 2024Molecular OncologyOpen Access

PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of reduced survival in patients

J.R. Ferreres Antònia Vinyals Rafael Campos-Martín Roderic Espín Sebastián Podlipnik Rúben Ramos Esther Bertrán Cristina Carrera Joaquim Marcoval Josep Malvehy Isabel Fabregat Susana Puig Àngels Fabra

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Abstract

Paired related homeobox 1 (PRRX1) is an inducer of epithelial-to-mesenchymal transition (EMT) in different types of cancer cells. We detected low PRRX1 expression in nevus but increased levels in primary human melanoma and cell lines carrying the BRAF

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Ferreres et al. (2024) studied this question.

synapsesocial.com/papers/68e6118db6db6435875a4359 https://doi.org/10.1002/1878-0261.13688

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