Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 7, 2024Journal of Personalized MedicineOpen Access

Monitoring of Immune Memory by Phenotypical Lymphocyte Subsets Identikit: An Observational Study in a Blood Donors’ Cohort

View Full Paper
Ask AI
Bookmark
Share

Authors

MDMarina Di DomenicoESEnrica SerretielloASAnnafrancesca Smimmo

Discussion

Loading...

Member takes

Overview

Observational study reveals ABO blood group variations in T cell subsets among vaccinated blood donors, highlighting phenotypic markers for precision medicine.

Key Points

  • Distinct lymphocyte subsets emerge across ABO blood groups in vaccinated individuals, showing significant percentage shifts in peripheral CD3, CD4, and CD8 T cells.
  • Multiparametric cytofluorimetric assay of blood donors aged 20–64 years tracked T cell maturation stages, evaluating markers including CD45RA, CCR7, and CD28.
  • Single-center observations highlight an immune memory identikit tied to blood groups, establishing an actionable biological baseline for precision medicine strategies.

Cite This Study

Domenico et al. (2024) studied this question.

synapsesocial.com/papers/68e6119bb6db6435875a4e0dhttps://doi.org/10.3390/jpm14070733
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1IMMUNOPHENOTYPING IN COVID 192024
  2. 2Analyzing the Relationship Between COVID-19 Susceptibility and Blood Group Variations: A Comprehensive Investigation into the Impact of ABO Blood Types on the Incidence, Severity, and Clinical Outcomes of the Disease2024
  3. 3Blood Group Variations in COVID-19 Convalescent Plasma and Regular Blood Donors: A Comparative Analysis in the Serbian Population2024 · 1 citations
  4. 4Immunological insights: assessing immune parameters in medical professionals exposed to SARS-CoV-22024
  5. 5Study of Peripheral Blood T‐Lymphocytes and Their Subpopulations in COVID‐19 Patients2025