Value-based trials aim to maximize the expected net benefit by balancing technology adoption decisions and clinical trial costs. Adaptive trials offer additional efficiency. This article provides guidance on determining whether a value-based sequential design is the best option for an adaptive 2-arm trial, illustrated through a case study.
No takes yet. Share an insight, caveat, or question.
Flight et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: