Hereditary cold-induced palmar erythema with dysesthesia: A novel entity with response to onabotulinumtoxinA injections

Erythema palmare hereditarium (EPH) is a rare, heritable subtype of palmar erythema (PE) that usually presents as a symmetric, nonpainful, nonpruritic erythema affecting the bilateral palms. EPH typically appears at birth or early childhood but can also appear later in life.1 To the best of our knowledge, this is one of the first reported cases of suspected EPH with Raynaud's phenomenon like cold-induced PE and dysesthesia responsive to onabotulinumtoxinA injections.2