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July 5, 2024Open Access

Supplementary Figure S6 from The Novel ATR Inhibitor Tuvusertib (M1774) Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs

Ukhyun Jo Yasuhiro Arakawa Astrid Zimmermann Daiki Taniyama Makito Mizunuma Lisa M. Jenkins Tapan K. Maity Suresh Kumar Frank T. Zenke Naoko Takebe Yves Pommier

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Abstract

This figure shows representative images in the treatment of TPT (topotecan) and M1774 in small cell lung cancer organoids, and profiling of cell viability and DNA-damage molecules after drug treatment.

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Jo et al. (2024) studied this question.

synapsesocial.com/papers/68e614b1b6db6435875a755e https://doi.org/10.1158/1535-7163.26190699

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1Supplementary Figure S6 from The Novel ATR Inhibitor Tuvusertib (M1774) Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs2024
2Supplementary Figure S6 from The Novel ATR Inhibitor M1774 Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs2024
3Supplementary Figure S6 from The Novel ATR Inhibitor M1774 Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs2024
4Supplementary Figure S7 from The Novel ATR Inhibitor Tuvusertib (M1774) Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs2024
5Supplementary Figure S7 from The Novel ATR Inhibitor Tuvusertib (M1774) Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs2024
6Supplementary Figure S4 from The Novel ATR Inhibitor Tuvusertib (M1774) Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs2024
7Supplementary Figure S4 from The Novel ATR Inhibitor Tuvusertib (M1774) Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs2024
8Supplementary Figure S5 from The Novel ATR Inhibitor Tuvusertib (M1774) Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs2024