⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

July 3, 2024The Journal of Organic Chemistry

Synthesis of Fully Substituted Pyrazoles with a Dicyanomethyl Group via DBU/Lewis Acid-Mediated Annulation of D–A Cyclopropanes with Arylhydrazines

Haiwen Li Wenzhe Cheng Jiaman Lv Cunde Wang

View Full Paper

Ask AI

Bookmark

Share

Abstract

The efficient synthesis of fully substituted pyrazoles with a dicyanomethyl group was developed via an annulation reaction of 2-aroyl D-A cyclopropanes with arylhydrazines in the presence of DBU/AlCl

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Li et al. (2024) studied this question.

synapsesocial.com/papers/68e617f5b6db6435875aa367 https://doi.org/10.1021/acs.joc.4c00919

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Direct Construction of 1,4-Dihydropyridazines and Parazoles via Annulation of Alkyl 2-Aroyl-1-chlorocyclopropanecarboxylates2024 · 6 citations
2Acetic Acid-Catalyzed (3 + 2) Cyclization of 2-Aroyl-3-aryl-1,1-dicyanocyclopropanes with Arylhydrazines: To trans -4-Dicyanomethyl-1,3,5-triaryl-4,5-dihydropyrazolesOriginal Research · 2023 · 11 citations
3Visible-Light-Promoted Intermolecular Annulation Toward Efficient Synthesis of Multisubstituted Pyrazoles2025
4Metal-Free Iodine-Catalyzed Synthesis of Fully Substituted Pyrazoles and Its SulphenylationOriginal Research · 2015 · 87 citations
5Base Induced Cyclocondensation of Arylhydrazines with α,β-Bis(methylthio)-α,β-unsaturated-1,4-diketones: A Novel Approach for the Synthesis of 1,3-Di(hetaryl/aryl)-4-methylthio-5-acyl-pyrazolesOriginal Research · 2026