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July 2, 2024Journal of Pharmacology and Experimental Therapeutics

Cannabinoid 2 receptor activation protects against diabetic cardiomyopathy through inhibition of AGE/RAGE-induced oxidative stress, fibrosis, and inflammasome activation

Hebaallah Mamdouh Hashiesh Sheikh Azimullah Nagoor Meeran M.F Dhanya Saraswathiamma Seenipandi Arunachalam Niraj Kumar Jha Bassem Sadek Ernest Adeghate Gautam Sethi Alia Albawardi Faisal Al Marzooqi Shreesh Ojha

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Abstract

Oxidative stress, fibrosis, and inflammasome activation from advanced glycation end product (AGE)-receptor of advanced glycation end product (RAGE) interaction contribute to diabetic cardiomyopathy (DCM) formation and progression. Our study revealed the impact of

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Hashiesh et al. (2024) studied this question.

synapsesocial.com/papers/68e61927b6db6435875ac474 https://doi.org/10.1124/jpet.123.002037

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