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July 1, 2024Journal of Medicinal Chemistry

Discovery of GPR84 Fluorogenic Probes Based on a Novel Antagonist for GPR84 Bioimaging

Yufeng Xiao Jing Chen Shaoxian Li Qing Zhang Yin Liu Linhai Chen Yadi Sun Min Gu Xin Xie Fajun Nan

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Abstract

GPR84 is a promising therapeutic target and biomarker for a range of diseases. In this study, we reported the discovery of BINOL phosphate (BINOP) derivatives as GPR84 antagonists. By investigating the structure-activity relationship, we identified

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Cite This Study

Xiao et al. (2024) studied this question.

synapsesocial.com/papers/68e61de3b6db6435875af9eb https://doi.org/10.1021/acs.jmedchem.4c00359

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