Antioxidant and neuroregenerative roles of Allium sativum L. in promoting central nervous health

This review examines the antioxidant properties of Allium sativum L. (A. sativum) and its implications for tissue regeneration, with a specific focus on the central nervous system (CNS).This review explores the existing research to highlight the antioxidant, anti-inflammatory, neuroprotective and regenerative effects of bioactive compounds within A. sativum, particularly allicin and its derivatives.Recent studies demonstrate that A. sativum has the potential to enhance the production of neurotrophic factors, promote neurogenesis, and improve overall neural function, which are essential parameters for the maintenance and recovery of the CNS.The key emphasis of this review is to highlight that A. sativum can support tissue regeneration in the CNS by modulating biochemical pathways involved in reducing oxidative stress and inflammation, which are essential for fighting neurodegenerative diseases such as Alzheimers, Parkinsons and Huntington diseases.The review also emphasizes the need for more robust clinical trials, improved formulations for enhanced bioavailability, and deeper investigations into the mechanisms of action of A. sativum on neural tissues.Conclusively, A. sativum diversity of roles in promoting the health of CNS offers promising aspects for developing natural, cost-effective therapeutic strategies for neurological conditions.Future research is encouraged to further validate garlic's benefits, optimize dosages, a nd integrate its use into conventional medical practices, enhancing outcomes for patients with CNS disorders.