Gastric perforation in neonates is a rare and serious issue. The condition usually occurs within the first week of life. Due to the high fatality rate, early diagnosis and prompt surgical intervention are required. Here, we describe two newborns who underwent emergency laparotomies for gastric perforation at the ages of 5 and 10 days, respectively. The first case did have sepsis during the recovery time, but it was successfully managed. The second neonate had stature disruption and biliary peritonitis. She eventually developed multi-organ failure syndrome and succumbed on the fourth day after the second laparotomy.
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