Supplementary Figures S5-S9 from Trisomy 8 Defines a Distinct Subtype of Myeloproliferative Neoplasms Driven by the MYC–Alarmin Axis

Nicole D. Vincelette; Xiaoqing Yu; Andrew Kuykendall; Jungwon Moon; Siyuan Su; Chia‐Ho Cheng; Rinzine Sammut; Tiffany N. Razabdouski; Hai V. Nguyen; Erika A. Eksioglu; Onyee Chan; Najla Al Ali; Parth Patel; Dae Hyun Lee; Shima Nakanishi; Renan B. Ferreira; Elizabeth Hyjek; Qianxing Mo; Suzanne Cory; Harshani R. Lawrence; Ling Zhang; Daniel J. Murphy; Rami S. Komrokji; Daesung Lee; Scott H. Kaufmann; John L. Cleveland; Seongseok Yun

doi:10.1158/2643-3230.26134485

Abstract

Figure S5. Changes in signaling in BM of trisomy 8+ TN-MF patient and MYC MF mice. Figure S6. Effects of silencing S100a9 in MYC-driven MF or overexpression of S100a9. Figure S7. Effects of inhibition of S100a9 or MYC in MYC-driven MF. Figure S8. Synthesis and Characterization of Tasquinimod. Figure S9. Synthesis and Characterization of MYCi975.

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Vincelette et al. (2024) studied this question.

synapsesocial.com/papers/68e62195b6db6435875b3656 https://doi.org/10.1158/2643-3230.26134485

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Supplementary Figures S5-S9 from Trisomy 8 Defines a Distinct Subtype of Myeloproliferative Neoplasms Driven by the MYC–Alarmin Axis

Abstract

Discussion

Cite This Study

Supplementary Figures S5-S9 from Trisomy 8 Defines a Distinct Subtype of Myeloproliferative Neoplasms Driven by the MYC–Alarmin Axis

Abstract

Discussion

Cite This Study

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