Supplementary Figures S1-S4 from Trisomy 8 Defines a Distinct Subtype of Myeloproliferative Neoplasms Driven by the MYC–Alarmin Axis

Nicole D. Vincelette; Xiaoqing Yu; Andrew Kuykendall; Jungwon Moon; Siyuan Su; Chia‐Ho Cheng; Rinzine Sammut; Tiffany N. Razabdouski; Hai V. Nguyen; Erika A. Eksioglu; Onyee Chan; Najla Al Ali; Parth Patel; Dae Hyun Lee; Shima Nakanishi; Renan B. Ferreira; Elizabeth Hyjek; Qianxing Mo; Suzanne Cory; Harshani R. Lawrence; Ling Zhang; Daniel J. Murphy; Rami S. Komrokji; Daesung Lee; Scott H. Kaufmann; John L. Cleveland; Seongseok Yun

doi:10.1158/2643-3230.26134488.v1

Abstract

Figure S1. Landscape of somatic mutations and cytogenetics in Moffitt MF cohort. Figure S2. Effects of enforced MYC expression in HSCs in vivo. Figure S3. MYC-induced changes in hematopoietic sub-populations and colony forming potential. Figure S4. The JAK/STAT, PI3K/AKT, MEK/ERK, and alarmin pathways in MYC-driven MF.

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Vincelette et al. (2024) studied this question.

synapsesocial.com/papers/68e62195b6db6435875b36ec https://doi.org/10.1158/2643-3230.26134488.v1

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Supplementary Figures S1-S4 from Trisomy 8 Defines a Distinct Subtype of Myeloproliferative Neoplasms Driven by the MYC–Alarmin Axis

Abstract

Discussion

Cite This Study

Supplementary Figures S1-S4 from Trisomy 8 Defines a Distinct Subtype of Myeloproliferative Neoplasms Driven by the MYC–Alarmin Axis

Abstract

Discussion

Cite This Study

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