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July 1, 2024Open Access

Supplementary Figure S1 from IL2 Targeted to CD8⁺ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity

Kelly D. Moynihan Manu P. Kumar Hussein Sultan Danielle C. Pappas Terrence Park Sherman M. Chin Paul Bessette Ruth Y. Lan Henry C. Nguyen Nathan D. Mathewson Irene Ni Wei Chen Yonghee Lee Sindy Liao-Chan Jessie Chen Ton N. Schumacher Robert D. Schreiber Yik A. Yeung Ivana M. Djuretic

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Abstract

Supplementary Figure S1: CD8+ T cells drive anti-tumor activity but NK cells are responsible for toxicity with not-α-IL2 therapy.

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Cite This Study

Moynihan et al. (2024) studied this question.

synapsesocial.com/papers/68e62195b6db6435875b36fb https://doi.org/10.1158/2159-8290.26134461.v1

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S1 from IL2 Targeted to CD8<sup>+</sup> T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity2024
2Supplementary Figure S5 from IL2 Targeted to CD8<sup>+</sup> T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity2024
3Supplementary Figure S5 from IL2 Targeted to CD8<sup>+</sup> T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity2024
4Supplementary Figure S8 from IL2 Targeted to CD8<sup>+</sup> T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity2024
5Supplementary Figure S8 from IL2 Targeted to CD8<sup>+</sup> T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity2024