Respiratory multiple infections by bacteria, viruses, fungi, and parasites in a COPD patient: A case report

SARS-CoV-2 is the causative agent of COVID-19, an infection that can manifest with mild to severe respiratory symptoms. A 70-year-old man with COVID-19 and COPD presented to a hospital complaining of breathing difficulties. A sample was taken, leading to the finding of the Acanthamoeba parasite. Stenotrophomonas maltophilia, a bacterium known for its resistance to most antibiotics and its significance as a nosocomial pathogen, was identified. Furthermore, for the first time, the Gloeotinia fungus was discovered as an endosymbiont of Acanthamoeba. The patient underwent successful treatment and was discharged from the hospital. Immunocompromised people should be concerned about the increasing incidence of nosocomial infections. The presence of Acanthamoeba should not be overlooked in respiratory disorders, as it has the potential to carry numerous pathogenic microorganisms as endosymbionts.