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Expanded hemodialysis (HDx), enabled by medium cut-off dialyzers, has been shown to increase the clearance of large middle molecules, compared to high flux hemodialysis (HF HD). Clearance of large middle molecular uremic toxins resulted in improved clinical outcomes. Patients and healthcare providers highly value the effects of new therapy on patient's quality of life.
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Ardila et al. (2024) studied this question.
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