Ss33-04 the Physical Activity Paradox in Cardiovascular Health: Evidence and Prevention

Introduction Recent research has increasingly demonstrated that the impact of physical activity varies based on its contextual setting. While the health benefits of physical activity during leisure time are widely acknowledged, the positive effects do not seem to extend to physical activity undertaken during working hours. This phenomenon is commonly referred to as the 'physical activity health paradox'. Materials and Methods This presentation aims to provide a comprehensive overview of the current evidence concerning the physical activity health paradox and its implications for cardiovascular disease prevention. Results A growing body of evidence has highlighted the potential for occupational physical activity to elevate the risk for cardiovascular disease and premature mortality. Various potential explanatory mechanisms have been suggested to shed light on the paradoxical effects between occupational and leisure time physical activity. These mechanisms encompass distinctions in factors such as type, intensity, duration and recovery patterns, resulting in divergent physiological responses. The research field faces methodological challenges related to exposure classification, reliance on subjective self-reports, and the presence of residual confounding, which remain subjects of debate. A limited number of studies have explored the impact of psychosocial job resources, such as job control and social support, as potential confounding variables or moderating factors. Conclusions The available body of evidence underscores the need for prevention guidelines that differentiate between various contexts of physical activity. Moreover, there is a call to tailor physical activity recommendations to subgroups facing particular needs.