O-082 Associations Between Job Control and Ischemic Heart Disease Mortality Among Swedish Men

Introduction Previous studies of low job control and IHD mortality have shown mixed results. The aim of this study is to investigate the association between job control and IHD mortality among Swedish men in their mid-50s followed up prospectively while accounting for potential confounding throughout the life-course. Methods The study is based on a register-linked cohort of 46,565 men who conscripted for the Swedish military in 1969/1970. Job control was measured using a job-exposure matrix (JEM) linked to the men’s registered occupations in 2005 and categorized into quintiles. They were followed regarding IHD deaths between 2006 and 2020. Cox regression models were used to estimate crude and adjusted hazard ratios. Models were adjusted for childhood socioeconomic position, factors from conscription at age 18 (divorced parents, psychiatric and musculoskeletal diagnoses, emotional control, cognitive ability, body mass index, blood pressure, alcohol consumption, and smoking), highest attained education, and occupational physical workload. Results Compared to the highest job control category, those with lower job control had an increased risk of IHD mortality in the crude model (HR 1.40, 95% CI 1.07-1.83 for medium high; HR 1.52, 95% CI 1.17-1.97 for medium; HR 2.13, 95% CI 1.66-2.73 for medium-low; and HR 2.92, CI 95% 2.31-3.69 for low). No significant associations remained in the adjusted model.“ Discussion This study contributes to previous research through the possibility to adjust for several important explanatory factors. The results are limited to older Swedish men. Conclusion Associations between low job control and IHD mortality appear to be non-causal and explained by other life-course factors.