Evaluation of The risk Factors Influencing The prognosis of Elderly Patients with Acute Poisoning Admitted to Poison Control Center, Ain Shams University Hospitals during 2022

Background: Poisoning in elderly people is frequently more severe, with greater complicationsand a higher risk of death. This study aimed to explore the risk factors affecting the prognosisof elderly individuals with acute intoxication. Subjects and Methods: A prospective studyinvolved all individuals sixty years of age or older with acute intoxication admitted to the PoisonControl Center of Ain Shams University Hospitals during 2022. Results: There were 72 elderlyindividuals with acute intoxication were enrolled in this study, with 56 survivors (77.78%) and16 non-survivors (22.22%). The majority of patients (83.33%) were between 60 and 74 years. Accidental intoxication and suicidal attempts were equally represented. The majority of acutelyintoxicated elderly patients had one or more underlying chronic comorbidities and the oral routewas more common. CVS drugs, CNS drugs, and pesticides were the major causes of acutepoisoning in elderly patients. CVS complications were the most frequent reason of ICUadmission in the elderly patients. The PSS score and APACHE II score were 3 ± 0 and 29.25 ±3.55 in the non-survivors, 1.52 ± 0.60, and 7.92 ± 1.81 in the survivors. Long hospitalization wascorrelated with a high APACHE II score. The presence of respiratory manifestations, the needfor mechanical ventilation, PSS score, and the APACHE II score were the independent riskfactors of poor prognosis. Conclusion: The presence of respiratory manifestations, the need formechanical ventilation, the PSS score, and the APACHE II score were the prognostic factors inelderly patients with acute poisoning. This study recommends taking precautions againstpoisoning in the elderly, particularly those who are at a high risk of suicid