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Inflammatory periodontal diseases are one of the most common dental diseases in the world, along with dental caries. In the modern concept of the development of inflammatory periodontal diseases, one of the important roles is assigned to the body's immune response to the action of periodontal pathogenic microorganisms. In modern scientific literature, the concept of cytokine development of inflammatory periodontal diseases has been formed and substantiated. Evaluation of the cytokine profile of oral and gingival fluids allows us to determine the activity and severity of the disease. Well-founded immunological and molecular genetic mechanisms for the development of inflammatory periodontal diseases, associated with the influence of cytokines, make it possible to adjust the complex treatment of inflammatory periodontal diseases, determine the direction of personalized therapy for patients, determine the effectiveness of the treatment and the prognosis of the disease.
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K.Z. et al. (2024) studied this question.
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