The Effect of Pre-Emptive Paracetamol on Postoperative Analgesic Requirement in Patients Undergoing Laparoscopic Surgery

Background: Pre-emptive use of paracetamol has been shown to reduce the need for postoperative analgesia in many patient groups; however, evidence supporting its role in laparoscopic surgery is lacking. Aim: To determine the effect of Pre-emptive paracetamol on post-operative analgesia requirement in patients undergoing laparoscopic surgery. Materials And Method: The randomised control trial was conducted at Dr. Kailash Narayan Singh Memorial Institute of Medical Sciences, Barabanki, Uttar Pradesh patients with physical status ASA I or ASA II were randomized into 2 groups. Group 1 received 1 gram of paracetamol intravenously 30 minutes before the operation; Group 2 was the control group and received 100 ml 0.9% normal saline. The VAS pain scores and analgesic needs within 6 hours after operation were compared among the two group. Results: Postoperative pain scores remained comparable among the two groups throughout most of the study. Postoperative Tramadol consumption was signicantly reduced in groups 1 and compared to group 2. Conclusion: Pre-emptive intravenous injection of paracetamol is effective in the treatment of post-operative pain after laparoscopic surgery