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Objective:To study the mode of clinical presentation, the role of tumor markers serum calcitonin and CEAin diagnosis and follow-up, and Surgery as a “curative” modality in treatment. Methods: In a retrospective analysis, 12 patients with medullary carcinoma thyroid who underwent surgical intervention between 2012 and 2015 at a tertiary care institute were included. Their medical records were retrieved and their follow-up records were analysed. Results: Surgical management with more of a radical approach than conservative gives better results and low recurrence in patients with medullary carcinoma thyroid. Tumor markers serum calcitonin and CEA were found to be reliable markers in the diagnosis and follow-up of patients with MTC. Conclusion: Medullary carcinoma thyroid, though rare and aggressive thyroid carcinoma can be cured with appropriate surgical management. The most common mode of clinical presentation in a case of medullary carcinoma thyroid is goiter. Serum calcitonin and CEA are reliable markers in establishing the diagnosis and during follow-up. Adjuvant radiotherapy can be offered for high-risk diseases.
Kumar et al. (Mon,) studied this question.