Malformations of the cortical system are associated with many neuropsychiatric manifestations. Gray matter heterotopia is a neuronal migration disorder characterized by the presence of normal gray matter neurons and glial cells, which are abnormally located in clusters within areas of white matter. Neurological manifestations such as seizure disorder, specific learning disability, intellectual disability, and stroke are the most common presentations. Psychiatric manifestations such as schizophrenia, anxiety, and depression although more common yet underreported or masked. Here, we present the report of a 17-year-old female with subependymal heterotopias, poor academic performance, and seizure disorder presenting with panic attacks.
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Vishnupriya Veeraraghavan (2024) studied this question.
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