143 Comparative Study Between Breast Conservative Surgery (BCS) and Modified Radical Mastectomy (MRM) in Early Stage of Breast Carcinoma in a Tertiary Care Hospital in Dhaka, Bangladesh

Aim To compare BCS and MRM in the treatment of early-stage breast carcinoma. Method This was a prospective observational study that involved 74 patients and was carried out in the department of surgery at Shaheed Suhrawardy Medical College & Hospital and Enam Medical College & Hospital, Dhaka, Bangladesh with an 18-months minimum follow-up. The time frame for inclusion was from July 2018 through July 2020. There were two patient groups, 37 patients in Group A who underwent breast conservative surgery and Group B was made up of 37 individuals who had MRM for early-stage breast carcinoma. Result With a mean age of 47.65 years in the BCS group and 48.19 years in the MRM group, the operative time for BCS was 1.04± 0.25 hours, whereas 3.20±0.48 hours for MRM. Statistically significant higher amount of post-operative drainage volume in MRM group compared to BCS group (p-value= 0.000). With an excellent aesthetic outcome rate in BCS group (p-value<0.0001) as well as better quality of life than MRM group. Conclusions Breast conservative surgery and modified radical mastectomy are both oncologically safe treatments for early-stage breast cancer with multidisciplinary approach. BCS offers less trauma, infection and hospital stay; better aesthetic outcome and quality of life than MRM, making it more deserving of being promoted clinically in the treatment of early-stage breast cancer.