601 SAVI SCOUT® vs Wire Guided Localization in Breast Conserving Surgery: A Symptomatic Breast Care Centre’s Experience

Aim Wire localization (WL) for nonpalpable tumours has been the gold standard localization technique in breast conserving surgery. However, issues such as patient discomfort, schedule inflexibility, and dislodgement can be encountered. SAVI SCOUT® (SSL), uses radar localization and can be inserted up to a month pre-operatively and was introduced in this institution in February 2023. This study aims to assess oncological outcomes as well user reported outcomes using WL vs SSL in a tertiary referral centre. Method A retrospective analysis was performed of all patients undergoing SSL wide local excision (WLE) and those undergoing WL WLE, for biopsy confirmed breast cancer, over 18 months. Primary outcomes were positive resection margin rate and re-excision rate. Results Eighty-two patients were included. Thirty-eight SSL and thirty-nine WL. Successful lesion excision was achieved in 100% of cases. Positive margin rate and re-excision rate was 15.8% for SSL (n=6) and 7.7% in WL (n=3) (p=0.45). 100% of breast radiologists agreed that SSL easier to place and schedule than WL, and believed it was more comfortable for patients than WL. Surgeon outcomes: 50% agreed tumours were easier to identify with SSL and probes were more accurately placed. 100% agreed that SSL led to less operation delays. Conclusions Positive outcomes were reported for SSL amongst users. However, a higher positive margin rate was seen in SSL when compared to WL (15.8% vs 7.7%) but was not statistically significant. A larger cohort of patients and increased operator experience is necessary to assess long term outcomes.