A prominent cutaneous eruption as a harbinger for aggressive systemic disease: Gamma-delta T-cell lymphoma

This is the authors' abstract. We don't add key points for this paper.

Primary cutaneous gamma-delta T-cell lymphoma (PCGDTCL) and hepatosplenic gamma-delta T-cell lymphoma (HSGDTCL) are rare and aggressive neoplasms, both with an overall 5-year survival of 10%.1,2 Even classic presentations of PCGDTCL and HGDTCL can be a diagnostic challenge due to the rarity of the conditions, variability of immunophenotypes presented in the literature, and variety of clinical presentations.1-4 Hemophagocytic lymphohistiocytosis (HLH) is a severe condition caused by dysregulated immune activation that can be triggered by various conditions such as infections, malignancy, rheumatologic disease, and drug hypersensitivity.