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In this study, we disclose the outcomes of the biological assessment of recently synthesized hybrids of ketoprofen with 2-phenylethylamines and 1,2,3,4-tetrahydroisoquinolines. These hybrids were obtained using an environmentally friendly method that minimizes the generation of waste products. The newly acquired hybrids were analysed to evaluate their antioxidant, anti-inflammatory, and anti-arthritic activities. Additionally, as potential drugs exhibiting favourable results, their experimental partition coefficient in a biphasic system of lipids and water (logP) was determined.
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Manolov et al. (2024) studied this question.
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