Himalayan Dioscorea villosa, a species of wild yam indigenous to the Himalayan region, has garnered attention for its diverse phytochemical composition and traditional medicinal uses. This comprehensive analysis explores the botanical, phytochemical, pharmacological, and ethnobotanical aspects of Himalayan Dioscorea villosa. The review synthesizes existing literature to provide insights into its taxonomical classification, morphological characteristics, and distribution patterns in the Himalayan ecosystem. It delves into the phytochemical profile of Dioscorea villosa, highlighting the presence of bioactive compounds such as diosgenin, flavonoids, alkaloids, and saponins. Moreover, the review examines the traditional uses of Himalayan Dioscorea villosa in folk medicine, shedding light on its purported therapeutic properties in treating various ailments. Furthermore, this analysis critically evaluates pharmacological studies elucidating the anti- inflammatory, antioxidant, antimicrobial, anticancer, and hormone-modulating activities of Dioscorea villosa extracts and isolated compounds. The pharmacokinetics and toxicological aspects of Himalayan Dioscorea villosa are also discussed, emphasizing the need for further research to ascertain its safety profile and dosage recommendations. Additionally, cultivation practices and conservation strategies for sustaining wild yam populations in the Himalayan region are addressed.
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Raj et al. (2024) studied this question.
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